Abstract Transpersonal therapy involves the integration of the mind, body, and spirit through the transcendence of the limitations of physical awareness toward expanded states of mindfulness. It has also been described as the melding of religious and spiritual traditions with modern therapy techniques {(Fukuyama} & Sevig, 1999). The fundamental principal of this approach is that humans are more than physical; they are also spiritual {(Smith}, 1995). Spirituality and disability are intricately interrelated, yet spirituality is too often the missing link in therapy for people with disabilities {(Boswell}, Knight, & Hamer, 2001). Transpersonal therapy can be a useful strategy for therapists, pastoral counselors, social workers, and rehabilitation counselors to assist people with disabilities in exploring Benson's (1996) “faith factor.” The faith factor is a combination of the relaxation response and remembered wellness. Exploration of the faith factor, within a transpersonal framework, can facilitate the development, or affirmation, of a spiritual self. As a result of this approach to therapy, people with physical, psychiatric, intellectual and cognitive disabilities can find hope, as well as a connection or reconnection with themselves, others, and a Higher Power.